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白三烯受体拮抗剂孟鲁司特钠治疗过敏性鼻炎的临床观察
引用本文:李秀梅,张达群. 白三烯受体拮抗剂孟鲁司特钠治疗过敏性鼻炎的临床观察[J]. 中国医药科学, 2012, 0(8): 30-31
作者姓名:李秀梅  张达群
作者单位:广东省茂名市人民医院药剂科;广东省茂名市人民医院耳鼻喉科
摘    要:目的探讨孟鲁司特钠治疗过敏性鼻炎的临床疗效。方法运用随机数字表法将186例过敏性鼻炎患者分为对照组和观察组各93例,治疗组应用孟鲁司特联合氯雷他定治疗,对照组单用氯雷他定治疗,疗程4周。结果治疗组总有效率为84.95%,显著高于对照组68.81%,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论孟鲁司特钠联合氯雷他定治疗过敏性鼻炎,疗效优于氯雷他定组,值得临床中广泛应用。

关 键 词:过敏性鼻炎  孟鲁司特  氯雷他定

Clinical curative effect of the Montelukast Soudium on the allergic rhinitis
LI Xiumei,ZHANG Daqun. Clinical curative effect of the Montelukast Soudium on the allergic rhinitis[J]. China Medicine and Pharmacy, 2012, 0(8): 30-31
Authors:LI Xiumei  ZHANG Daqun
Affiliation:1.Department of Pharmacy,the People’s Hospital of Maoming City,Maoming 525000,China;2. Department of ENT, the People’s Hospital of Maoming City,Maoming 525000,China
Abstract:Objective To explore the clinical curative effect of the Montelukast Soudium on the allergic rhinitis. Methods 186 cases which treatment of allergic rhinitis were randomly divided into the treatment group and the control group, the treatment group was administered orally with MontelukastSoudium and loratadine, the control group was given with loratadine. Treatment continued for 4 weeks. Results The total effective rate of the treatment group was 84.95%, significantly higher than those in the control group 68.81%(P < 0.05); The difference of adverse reaction rate in two groups had no actually statistical significance(P > 0.05). Conclusion In reatment of allergic rhinitis,the MontelukastSoudium and loratadine in conjunction, the treatment effect is better ,which is worth widely used.
Keywords:Allergic rhinitis  MontelukastSoudium  Loratadine
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