肺血管肉瘤的诊断与治疗——附1例报告并文献复习

目的复习肺血管肉瘤的临床表现、病理形态学特点、诊断、鉴别诊断和治疗。方法结合文献报道,回顾性分析5例肺血肉瘤患者临床资料。结果肺血管肉瘤临床症状为胸痛、咳嗽、咯血,肺内多发结节、斑片影,病理检查瘤体主要为血管内衬异型的瘤细胞(血管内皮细胞),可见相互吻合大小不一形态不规则的血管网,免疫组化CD34、CD31和vimentin阳性。结论肺血管肉瘤是罕见的软组织高度恶性肿瘤,预后差。肺血管肉瘤需与肺腺癌、肺结核、真菌等疾病鉴别。

Diagnosis and treatment of pulmonary angiosarcoma(1 case report and a literature review)

Objective To review the clinical features, pathological characteristics, diagnosis and differential diagnosis and treatment of pulmonary angiosarcoma. Methods The clinical data in 5 cases was retrospectively analyzed with a literature review. Results The clinical symptoms of pulmonary angiosarcoma were chest pain.cough and emptysis. Multiple nodules and plaque may be seen on Chest CT. Microscopically,the tumor was composed of blood vessel endothelium cells with obvious dysplasia, many irregular blood vessels varied in size were inosculated each other and formed vascular web. The immunohistochemical results showed positive CD34.CD31 and vimentin positive in cases. Conclusion Pulmonary angiosarcoma is a rare and high malignant soft tumor with poor prognosis, the diagnosis mainly depends on pattology. It needs to be differential diagnosted with lung adenocarcinoma, pulmonary tuberculosis, and mycosis etc.