补肾中药联合生物反馈电刺激改善全子宫切除术后性功能障碍及对患者盆底功能的影响

目的:观察补肾中药联合生物反馈电刺激改善全子宫切除术后性功能障碍和盆底功能的临床效果。方法:将160例行全子宫切除的患者作为观察对象,按照随机数字表法分为A、B、C、D组各40例。所有患者均实施常规术后康复锻炼,在此基础上A组不采用其他任何干预措施,B组给予补肾中药治疗,C组给予生物反馈电刺激治疗,D组给予补肾中药联合生物反馈电刺激治疗。比较治疗前(T0)、治疗后6个月(T1)、治疗后12个月(T2)四组患者中医证候积分、血清性激素水平[雌二醇(E₂)、促黄体生成素(LH)、促卵泡生成激素(FSH)]、盆底肌电生理指标、性功能[女性性功能量表(FSFI)]水平差异。结果:T0时,四组各中医证候积分、血清性激素水平、盆底肌电生理指标、FSFI评分比较差异无统计学意义(P>0.05)。T1、T2时,四组中医证候积分、LH、FSH水平及Ⅰ、Ⅱ类盆底肌肌纤维疲劳度均低于T0时,且B组、C组、D组均低于A组,D组低于B、C组(P<0.05); 四组血清E₂、FSFI评分及Ⅰ、Ⅱ类盆底肌肌纤维的肌电平均值均高于T0时,且B、C、D组均高于A组,D组高于B、C组(P<0.05)。结论:补肾中药联合生物反馈电刺激能有效改善全子宫切除术后患者血清性激素水平,改善性功能障碍及盆底功能。

Clinical study of kidney-tonifying Chinese medicine combined with biofeedback electrical stimulation on improving sexual dysfunction and pelvic floor function after total hysterectomy

Objective:To observe the clinical effects of kidney-tonifying Chinese medicine combined with biofeedback electrical stimulation on improving sexual dysfunction and pelvic floor function after total hysterectomy.Methods:160 patients who underwent total hysterectomy were selected as the observation subjects,and they were divided into groups A,B,C and D according to the random number table method,with 40 cases in each group.All patients underwent routine postoperative rehabilitation exercise,and on this basis,group A did not use any other interventions,group B was given kidney-tonifying Chinese medicine,group C adopted biofeedback electrical stimulation and group D was given kidney-tonifying Chinese medicine combined with biofeedback electrical stimulation.Before treatment(T0),at 6 months after treatment(T1)and at 12 months after treatment(T2),the scores of TCM syndromes,levels of serum sex hormones [estradiol(E₂),luteinizing hormone(LH),follicle-stimulating hormone(FSH)],pelvic floor muscle electrophysiological indicators and sexual function [Female Sexual Function Inventory(FSFI)] were compared among the four groups.Results:At T0,there were no statistical differences in the scores of TCM syndromes,levels of serum sex hormones,pelvic floor muscle electrophysiological indicators and FSFI score among the four groups(P>0.05).At T1 and T2,the TCM syndromes scores,LH and FSH and type Ⅰ and type Ⅱ pelvic floor muscle fiber fatigue degrees in the four groups were lower than those at T0,and the above indicators were all lower in groups B,C and D than group A,and were lower in group D than group B and group C(P<0.05).The levels of serum E₂,FSFI score and the average electromyogram values of type Ⅰ and type Ⅱ pelvic floor muscle fibers in the four groups were all higher than those at T0,and the above indicatorsin groups B,C and D were higher compared to group A,and indicators in group D were higher compared to group B and group C(P<0.05).Conclusion:Kidney-tonifying Chinese medicine combined with biofeedback electrical stimulation can effectively promote the recovery of serum sex hormones in patients after total hysterectomy,and improve the sexual dysfunction and pelvic floor function.