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| 生长抑素受体在乳腺癌组织中表达及其临床意义 | |
| 引用本文： | 王少华,于泽平,李宁,杨小冬,张新华,孙桂秦,黎介寿. 生长抑素受体在乳腺癌组织中表达及其临床意义[J]. 实用临床医药杂志, 2006, 10(3): 5-7 |
| 作者姓名： | 王少华 于泽平 李宁 杨小冬 张新华 孙桂秦 黎介寿 |
| 作者单位： | 南京军区南京总医院解放军普通外科研究所,江苏,南京,210002;南京军区南京总医院解放军普通外科研究所,江苏,南京,210002;南京军区南京总医院解放军普通外科研究所,江苏,南京,210002;南京军区南京总医院解放军普通外科研究所,江苏,南京,210002;南京军区南京总医院解放军普通外科研究所,江苏,南京,210002;南京军区南京总医院解放军普通外科研究所,江苏,南京,210002;南京军区南京总医院解放军普通外科研究所,江苏,南京,210002 |
| 摘 要： | 目的研究生长抑素受体(SSTR)在原发性浸润性乳腺癌组织中的表达情况,以及与临床病理因素的关系。方法应用免疫组化法(IHC)检测82例原发性乳腺浸润性导管癌组织中SSTR的表达,分析其与临床病理因素的关系。结果原发性乳腺浸润性导管癌组织中SSTR阳性表达率为74.4%(61/82)。SSTR阳性表达强度与年龄(P>0.05)、肿瘤大小(P>0.05)无关,不同肿瘤病理分期(P<0.001)、分化程度(P<0.05)的肿瘤组织中SSTR表达强度有显著性差异。结论原发性乳腺浸润性导管癌组织中SSTR阳性表达率为74.4%,因此,对大多数疑为乳腺癌的患者可应用生长抑素受体显像技术(SRS)进行筛选。 |
| 关 键 词： | 生长抑素受体 原发性乳腺浸润性导管癌 免疫组化 |
| 文章编号： | 1672-2353(2006)02-0005-03 |
EXPRESSION OF SOMATOSTATIN RECEPTOR IN HUMAN BREAST CARCINOMA AND ITS CLINICAL SIGNIFICANCE |
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| WANG Shao-hua,YU Ze-ping,LI Ning,YANG Xiao-dong,ZHANG Xin-hua,SUN Gui-qin,LI Jie-shou. EXPRESSION OF SOMATOSTATIN RECEPTOR IN HUMAN BREAST CARCINOMA AND ITS CLINICAL SIGNIFICANCE[J]. Journal of Clinical Medicine in Practice, 2006, 10(3): 5-7 | |
| Authors: | WANG Shao-hua YU Ze-ping LI Ning YANG Xiao-dong ZHANG Xin-hua SUN Gui-qin LI Jie-shou |
| Abstract: | Objective To determinate whether human primary breast invasive ductal carcinoma(HPBIDC) expresses somatostatin receptor(SSTR).Methods SSTR expression in 82 patients with invasive duct carcinoma of breast was determined by immunohistochemistry and its correlation with clinical and pathological facts was analyzed.Results IHC analyses revealed that SSTR was expressed in HPBIDC(61/82,74.4%).A significant correlation was found between SSTR expression and tumor stage(P<0.001),tumor differentiation(P<0.05),and there are no statistically significant relationship between the expression of SSTR,age(P>0.05),and tumor size(P>0.05).Conclusions SSTR expression ratio in invasive ductal carcinoma of breast is 74.4%(61/82). |
| Keywords: | somatostatin receptor human primary breast invasive ductal carcinoma immunohistochemistry |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |