| 香菇多糖腔内注射治疗恶性胸腔积液22例临床观察 |
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| 引用本文： | 田鑫,王伟钢,贾立群.香菇多糖腔内注射治疗恶性胸腔积液22例临床观察[J].医学综述,2010,16(12). |
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| 作者姓名： | 田鑫 王伟钢 贾立群 |
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| 作者单位： | 1. 卫生部中日友好医院国际医疗部,北京,100029
2. 卫生部中日友好医院肿瘤科,北京,100029 |
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| 摘 要： | 目的观察香菇多糖(LNT)腔内注射治疗恶性胸腔积液(MPE)的疗效。方法将43例恶性胸腔积液患者随机分为两组。治疗组22例,接受香菇多糖腔内注射治疗,对照组21例接受白细胞介素2腔内注射治疗。结果治疗组胸腔积液改善有效率为63.64%,对照组为57.14%,两组比较差异无统计学意义(P>0.05);治疗组患者生活质量改善优于对照组(P<0.05),不良反应发生率低于对照组。结论 LNT腔内注射能有效控制MPE,提高患者生活质量,是治疗MPE的有效药物之一。
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| 关 键 词： | 香菇多糖 白细胞介素2 恶性胸腔积液 |
Clinical Study of Intrapleural Injection of Lentinan for Malignant Pleural Effusion |
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| Abstract: | Objective To observe the efficacy of lentinan in the malignant pleural effusions.Methods Forty-three patients with malignant pleural effusions were dirided into two groups.The treatment group included 22 cases for the treatment by lentinan,while the contrast group covered 21 cases for the treatment by interleukin-2.Results The effective rate of pleural fluid curing,the treatment group is 63.64%,the contrast group is 57.14%,the two sets have not distinct difference(P>0.05).About the improvement of quality of life,the treatment group is better than the contrast group(P<0.05),moreover,the adverse is low.Conclusion Lentinan can effectively control the malignant pleural effusions and improve the life quality of patients. |
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| Keywords: | Lentinan Interleukin-2 Malignant pleural effusions |
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