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| Localized intra-abdominal fibromatosis of the small bowel mimicking a gastrointestinal stromal tumor： A case report | |
| 引用本文： | Colombo P,Rahal D,Grizzi F,Quagliuolo V,Roncalli M. Localized intra-abdominal fibromatosis of the small bowel mimicking a gastrointestinal stromal tumor： A case report[J]. World journal of gastroenterology : WJG, 2005, 11(33): 5226-5228. DOI: 10.3748/wjg.v11.i33.5226 |
| 作者姓名： | Colombo P Rahal D Grizzi F Quagliuolo V Roncalli M |
| 作者单位： | Department of Pathology Istituto Clinico Humanitas Rozzano Milan Italy,Department of Pathology Istituto Clinico Humanitas Rozzano Milan Italy,Scientific Direction Istituto Clinico Humanitas Rozzano,Milan,Italy,Department of General Surgery Istituto Clinico Humanitas,Rozzano,Milan,Italy,Department of Pathology Istituto Clinico Humanitas,Rozzano,Milan Italy University of Milan School of Medicine Milan,Italy |
| 摘 要： | Intra-abdominal fibromatosis (IAF) is a benign mesenchymal lesion that can occur throughout the gastrointestinal tract. Although rare, it is the most common primary tumor of the mesentery and can develop at any age. We describe a rare case of primary IAF involving the mesentery and small bowel which clinically, macroscopically and histologically mimicked malignant gastrointestinal stromal tumor (GIST). This report highlights the fact that benign IAF can be misdiagnosed as a malignant GIST localized in the mesentery or arising from the intestinal wall. Their diagnostic discrimination is essential because of their very different biological behaviors and the fact that the introduction of effective therapies involving tyrosine kinase inhibitor STI571 (imatinib mesylate) has greatly changed the clinical approach to intra-abdominal stromal spindle cell tumors. |
| 关 键 词： | 腹部纤维瘤 小肠疾病 胃肿瘤 肠肿瘤 病例报告 |
| 收稿时间： | 2004-10-13 |
Localized intra-abdominal fibromatosis of the small bowel mimicking a gastrointestinal stromal tumor: a case report |
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| Colombo Piergiuseppe,Rahal Daoud,Grizzi Fabio,Quagliuolo Vittorio,Roncalli Massimo. Localized intra-abdominal fibromatosis of the small bowel mimicking a gastrointestinal stromal tumor: a case report[J]. World journal of gastroenterology : WJG, 2005, 11(33): 5226-5228. DOI: 10.3748/wjg.v11.i33.5226 | |
| Authors: | Colombo Piergiuseppe Rahal Daoud Grizzi Fabio Quagliuolo Vittorio Roncalli Massimo |
| Affiliation: | 1. Department of Pathology,Istituto Clinico Humanitas,Rozzano,Milan,Italy 2. Scientific Direction,istituto Clinico Humanitas,Rozzano,Milan,Italy 3. Department of General Surgery,Istituto Clinico Humanitas,Rozzano,Milan,Italy 4. Department of Pathology,Istituto Clinico Humanitas,Rozzano,Milan,Italy;University of Milan School of Medicine,Milan,Italy |
| Abstract: | Intra-abdominal fibromatosis (IAF) is a benign mesenchymal lesion that can occur throughout the gastrointestinal tract. Although rare, it is the most common primary tumor of the mesentery and can develop at any age. We describe a rare case of primary IAF involving the mesentery and small bowel which clinically, macroscopically and histologically mimicked malignant gastrointestinal stromal tumor (GIST). This report highlights the fact that benign IAF can be misdiagnosed as a malignant GIST localized in the mesentery or arising from the intestinal wall. Their diagnostic discrimination is essential because of their very different biological behaviors and the fact that the introduction of effective therapies involving tyrosine kinase inhibitor STI571 (imatinib mesylate) has greatly changed the clinical approach to intra-abdominal stromal spindle cell tumors. |
| Keywords: | Intra-abdominal fibromatosis Gastrointestinal tract Gastrointestinal stromal tumor |
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