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白花丹地上部分的化学成分
引用本文:黄小燕,谭明雄,吴强,陈勇,王恒山. 白花丹地上部分的化学成分[J]. 中国药学, 2008, 17(2): 144-147
作者姓名:黄小燕  谭明雄  吴强  陈勇  王恒山
作者单位:广西师范大学 化学化工学院 药用资源化学与药物分子工程重点实验室,广西桂林541004
基金项目:国家重点基础研究发展计划(973计划) , 广西自然科学基金 , Project of the Key Laboratory of Medicinal Chemical Resources and Molecular Engineering Guangxi Normal University
摘    要:研究白花丹Plumbago zeylanica L.地上部分的化学成分。应用各种色谱方法分离;用波谱学方法特别是二维核磁共振波谱的方法确定结构。从白花丹地上部分分离鉴定了7个化合物,分别是:1β,3β,11α-trihydroxy-urs-12-ene(1),androsta-1,4-diene-3,17-dione(2),异信浓柿醇酮(3),neoechinulin A(4),harman(5),ergostadiene-3β,5α,6β—triol(6),N-(N-benzoyl-S-phenylalaninyl)-S-phenylalaninol(7)。化合物1为新化合物,化合物2,4-7均为首次从该属植物中分离得到。

关 键 词:白花丹属  白花丹  化学成分

Chemical constituents from the aerial parts of Plumbago zeylanica L.
Xiao-Yan Huang,Ming-Xiong Tan,Qiang Wu,Yong Chen,Heng-Shan Wang. Chemical constituents from the aerial parts of Plumbago zeylanica L.[J]. Journal of Chinese Pharmaceutical Sciences, 2008, 17(2): 144-147
Authors:Xiao-Yan Huang  Ming-Xiong Tan  Qiang Wu  Yong Chen  Heng-Shan Wang
Affiliation:( Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, College of Chemistry & Chemical Engineering, Guangxi Normal University, Guilin 541004, China )
Abstract:To investigate the chemical constituents from the aerial parts of Plumbago zeylanica L. The chemical constituents were isolated by various column chromatographic methods and the structures were elucidated by various spectroscopic methods, especially 2D- NMR spectra. A new tfiterpenoid, 1β,3β,1 1α-trihydroxy-urs-12-ene (1), together with six known compounds, androsta-l,4-diene-3,17- dione (2), isoshinznolone (3), neoechinulin A (4), harman (5), ergostadiene-3β,5α,6β-triol (6) and N-(N'-benzoyl-S-phenylalaninyl)-S- phenylalaninol (7) were isolated from the aerial parts ofP. zeylanica. Compound 1 was a new compound, and compounds 2, 4-7 were obtained from this genus for the first time.
Keywords:Plumbago  Plumbago zeylanica L.  Chemical constituents
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