吸烟与支气管哮喘研究进展

吸烟是支气管哮喘(简称哮喘)发病的危险因素之一。吸烟的哮喘患者在临床表型、影像学表现和气道炎症方面与普通哮喘患者不同。吸烟可加速肺功能下降,加重哮喘病情。吸烟哮喘患者气道重塑更严重。吸烟降低哮喘患者激素治疗敏感性。

Further understanding of specific immunotherapy in bronchial asthma

Current pharmacotherapy, such as inhaled corticosteroids (ICS), provides powerful anti-symptomatic benefits in bronchial asthma (asthma). However, it does not cure or modify the natural course of allergic disease. Immunotherapy targets the immunological background in asthma, including pathological activation of Th2 cells, thus providing therapeutic potency for the variety of allergic diseases observed simultaneously in allergic individuals, and possibly modifying the natural course of allergic diseases.Subcutaneous immunotherapy (SLIT) has been shown to be as effective for allergic rhinitis and asthma as SCIT, and SLIT is more safer and convenient. New forms of immunotherapy are also being developed. It is hoped that the novel approaches will become more sophisticated and provide better efficacy,thus making immunotherapy more important therapy for asthma.