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Emergence of Clostridium difficile infection in tuberculosis patients due to a highly rifampicin-resistant PCR ribotype 046 clone in Poland |
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| Authors: | P. Obuch-Woszczatyński G. Dubiel C. Harmanus E. Kuijper U. Duda D. Wultańska A. van Belkum H. Pituch |
| Affiliation: | 1. Department of Medical Microbiology, Medical University of Warsaw, 5 Cha?ubiński Street, 02-004, Warsaw, Poland 2. Specialized Hospital of Lung Diseases and Tuberculosis, Bystra, Poland 3. Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands 4. Sanitary Epidemiological Station, Bielsko-Bia?a, Poland 5. R&D Microbiology, bioMérieux, La Balme-les-Grottes, France |
| Abstract: | Clostridium difficile infection (CDI) is a major cause of nosocomial diarrhea. CDI is known to develop after antibiotic administration, but anti-tuberculosis agents have rarely been implicated. We documented an outbreak caused by a highly rifampicin-resistant C. difficile strain of polymerase chain reaction (PCR) ribotype 046 in patients with active tuberculosis. |
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