Transcriptional suppression of the adrenal cortical peripheral-type benzodiazepine receptor gene and inhibition of steroid synthesis by ginkgolide B |
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| Authors: | Amri Hakima Drieu Katy Papadopoulos Vassilios |
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| Affiliation: | Division of Hormone Research, Department of Cell Biology, Georgetown University Medical Center, 3900 Reservoir Road, Washington, DC 20057, USA. |
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| Abstract: | |
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| Keywords: | CAT, chloramphenicol transferase Cyp17, cytochrome P450 17α-hydroxylase dbcAMP, N6,2′-O-dibutyryladenosine 3′:5′-cyclic monophosphate DTT, dithiothreitol EGb 761, standardized Ginkgo biloba leaf extract EMSA, electrophoretic mobility shift assay βGal, β-galactosidase GKA, purified ginkgolide A GKB, purified ginkgolide B PBR, peripheral-type benzodiazepine receptor PCR, polymerase chain reaction PMSF, phenylmethylsulfonyl fluoride and VDAC, voltage-dependent anion channel protein |
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