淋巴瘤治疗后残留淋巴结超声与PET/CT检查的对比研究

目的 比较淋巴瘤治疗后残留淋巴结超声特征与PET/CT显像特点,探讨其在淋巴瘤疗效检测上的价值.方法 对32例淋巴瘤患者治疗后77枚残留浅表淋巴结分别进行彩色多普勒超声检查和PET/CT检查,采用两种方法判断肿瘤残余情况,并结合临床及残留淋巴结穿刺活检的病理结果进行比较分析.结果 在77枚淋巴结中超声判断肿瘤残余情况73枚与病理或临床结果一致(占94.8%),PET/CT判断情况75枚与病理或临床结果一致(97.4%).超声显示有肿瘤残余组较无肿瘤残余组淋巴结长径(L)/短径(S)值小、血供丰富、血流速度快、R1低(P＜0.05).PET/CT检查显示有肿瘤残余组淋巴结处于高代谢状态,无肿瘤残余组淋巴结内无异常高代谢.有肿瘤残余组淋巴结超声指标与PET/CT显示高代谢间有一定关联.结论 两种方法诊断准确率较高,均对临床疗效评估有重要实用价值,超声检查可以作为常规检查手段.

Comparison of ultrasound and PET/CT in detecting lymphomatous lymph nodes after chemotherapy

Objective To observe ultrasonic and PET/CT features of malignant lymphoma after chemotherapy and to determine the value in assessment of lymphoma treatment response.Methods Seventy-seven lymph nodes in 32 patients were observed and measured with color Doppler ultrasound and PET/CT after chemotherapy comparing with pathologic results.Results Seventy-two lymph nodes were exactly certified by ultrasound(94.8%),and seventy-five nodes were exactly confirmed by PET/CT(97.4%).There were significant differences in L/S,blood supply type,Vmax,Vmin,RI(P＜0.05)between nodes groups with and without residual tumor.The PET/CT inspection demonstrates that lymph nodes with residual tumor was in the high metabolism condition.The positive nodes'index of ultrasound were connected with their metabolism condition.Conclusions The two methods all have high rate of accuracy.Ultrasound can be used as normal method in assessment of lymphoma treatment response.