静脉注射地塞米松预防下颌阻生智齿拔除术后并发症的疗效评价

目的：探讨地塞米松对下颌阻生智齿拔除术后并发症的预防。方法：选择96名双侧对称性下颌阻生智齿拔除术患者，术前10min随意选择一侧静脉注射地塞米松5mg(1ml)，为用药组；另一侧注射生理盐水1ml，为对照组。分别记录术前及术后第1、2、3、5d面部肿胀、疼痛及张口困难情况，并进行统计学分析。结果：术后用药组面部肿胀百分率最大为3.16%，对照组为6.09%，两组对比有显著性差异（P＜0.001)；对术后疼痛及张口困难的影响均无显著性差异（P＞0.05)。结论：地塞米松能明显改善下颌阻生智齿拔除术后的面部肿胀，但对疼痛及张口困难无预防作用。

Evaluation of Dexamethasone Intravenously for Prevention of Postsurgical Complication of Mandibular Impacted Teeth Removal

Objective:To evaluate the effect of dexamethasone on prevention of postsurgical complication of mandibular impacted teeth removal.Methods:Ninety-six patients with bilaterally symmetrical impacted third molars removal were administered intravenously with five mg(1ml)of dexamethasone at approximately 10 minutes preoperatively and 1 ml of sterile water was used as a control in a similar fashion.Use of dexamethasone preparation was randomized to side( right or left ). Data were collected preoperatively and at 1?2?3?5 days after operation.Measurements were repeated for the second surgical treatment.Results:The postsurgical swelling was 3.16% of patients in dexamethasone group and 6.09% in control group.There was significant difference between the two groups (P<0.001).The postoperative pain and truisms was no significant difference(P>0.05).Conclusion:Dexamethasone can decrease postsurgical swelling, but can not decrease postsurgical pain and truisms.