| Effects of acupotomy on the activity of osteoclasts and osteoblasts in the subchondral bone of rabbits with early and mid-stage knee osteoarthritis modelsOA |
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| 作者姓名： | Mira Lee Yan Guo Xilin Chen Longfei Xing Wei Zhang Lia Chang Changqing Guo |
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| 作者单位： | 1. School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine;2. Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine;3. Massage Department, Beijing University of Chinese Medicine Third Affiliated Hospital;4. Graduate School of Environmental Studies, Seoul National University |
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| 基金项目： | supported by the Beijing Municipal Natural Science Foundation (7192110); |
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| 摘 要： | Objective: To investigate whether acupotomy could inhibit subchondral bone remodeling in knee osteoarthritis(KOA) rabbits by regulating the activity of osteoblasts and osteoclasts.Methods: KOA rabbits were prepared by immobilization for 6 and 9 weeks by Videman method. Nine groups of rabbits(control, 6 weeks and 9 weeks model, 6 weeks and 9 weeks acupotomy, 6 weeks and 9 weeks electroacupuncture, and 6 weeks and 9 weeks drug groups) received acupotomy, electroacupuncture and risedronate sodium i...
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