颅内破裂动脉瘤手术时机和预后关系 |
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引用本文: | 张更申,吴国彪,范振增,孙国柱. 颅内破裂动脉瘤手术时机和预后关系[J]. 脑与神经疾病杂志, 2008, 16(6) |
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作者姓名: | 张更申 吴国彪 范振增 孙国柱 |
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作者单位: | 1. 河北医科大学第二医院神经外科,石家庄,050000 2. 河北医科大学第一医院神经外科 |
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摘 要: | 目的:探讨颅内破裂动脉瘤手术时机与预后关系。方法:将2003年1月~2007年7月我院手术夹闭387例颅内破裂动脉瘤患者按入院时Hunt&Hess分级分为Ⅰ~Ⅱ级(283例)、Ⅲ级(75例)和Ⅳ~Ⅴ级(29例)三组,各组依据手术距发病时间不同再分为早期(发病后0~3d)、中期(4~10d)和晚期(11d~)手术治疗三个亚组。比较接受不同时段手术治疗患者延迟性缺血性神经功能障碍、脑积水及出院时结果良好(GOS≥4)发生率。结果:Ⅰ~Ⅱ级患者早、中和晚期手术良好率分别为90.2%(46/51)、82.0%(41/50)和83.5%(152/182)。Ⅲ级患者早、中和晚期手术良好率分别为56.0%(14/25)、80.0%(4/5)和57.8%(26/45)。Ⅳ~Ⅴ级患者早、中和晚期手术良好率分别为46.2%(6/13)、20.0%(1/5)和0.0%(0/11)。Ⅰ~Ⅱ级和Ⅲ级接受不同时间段手术夹闭治疗患者的延迟性缺血性神经功能障碍、脑积水及出院时结果良好发生率无统计学差异。Ⅳ~Ⅴ级患者早期手术结果良好率显著高于非早期手术组(P=0.026),而延迟性缺血性神经功能障碍、脑积水无显著差别。结论:Hunt&HessⅠ~Ⅲ级的患者早、中和晚期手术均可,Ⅳ~Ⅴ级患者应早期接受手术治疗。
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关 键 词: | 颅内动脉瘤破裂 蛛网膜下腔出血 手术时机 延迟性缺血性神经功能障碍 脑积水 |
The relation between surgical timing and clinical prognosis on ruptured intracranial aneurysms |
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Affiliation: | ZHANG Geng-shen; WU Guo-biao; FAN Zhen-zeng; et al. Department of Neurosurgery; The 2nd hospital of HeBei Medical University; Shijiazhuang 050000; China; |
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Abstract: | Objective:To investigate the correlation between surgical timing and clinical prognosis on ruptured intracranial aneurysm.Methods:387 cases of ruptured intracranial aneurysms admitted in our hospital from Jan-2003 to Jul-2007,whom clipping operations had been completed on,were divided into gradeⅠ~ⅡGroup(283cases),grade ⅢGroup(75cases)and Ⅳ~ⅤGroup(29cases)classified on the base of the Hunt&Hess grade on admission.Each group was then divided into early surgery subgroup defined as operation performed within th... |
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Keywords: | ruptured intracranial aneurysm subarachnoid hemorrhage operation timing delayed ischemic neurological deficit hydrocephalus |
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