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大剂量孕激素在年轻患者早期子宫内膜癌治疗中的应用
引用本文:刘天凤,尹福波,庄炎. 大剂量孕激素在年轻患者早期子宫内膜癌治疗中的应用[J]. 肿瘤基础与临床, 2007, 20(3): 262-264
作者姓名:刘天凤  尹福波  庄炎
作者单位:山东大学山东省立医院妇科,山东,济南,250021;山东大学山东省立医院妇科,山东,济南,250021;山东大学山东省立医院妇科,山东,济南,250021
摘    要:
目的 探讨年轻女性子宫内膜癌的诊断、治疗及预后的特点.方法 口服大剂量孕激素,根据子宫内膜逆转情况调节药物用量.结果 子宫内膜癌逆转,并IVF-ET受孕成功,分娩1个正常女婴.结论 年轻妇女子宫内膜癌多与月经不调、不孕不育、多囊卵巢综合征等高危因素有关;以手术治疗为主,分化好病理分期Ⅰ期、有迫切生育要求者,可在严密观察下行药物保守治疗并助孕.

关 键 词:年轻妇女  子宫内膜癌  治疗  禁忌症  副作用  预后
文章编号:1673-5412(2007)03-0262-03
收稿时间:2006-10-09
修稿时间:2006-10-09

High-Dose Progestin Applicatin in Young Patients with Early Endometrial Carcinoma
Liu Tianfeng,Yin Fubo,Zhuang Yan. High-Dose Progestin Applicatin in Young Patients with Early Endometrial Carcinoma[J]. Journal of Basic and Clinical Oncology, 2007, 20(3): 262-264
Authors:Liu Tianfeng  Yin Fubo  Zhuang Yan
Affiliation:Department of Gynecology, Shandong Provincial Hospital ,Shandong University, Jinan 250021, China
Abstract:
Objective To investigate the diagnosis,therapy and prognosis of endometrial carcinoma(EC) in young women.Methods Took oral high-dose progestin,adjusted the dosage according to the reversion of endometrium.Results The endomet-Rium had a complete response and the patient became pregnant with the aid of ICSI-ET and deliverd a normal infant.Conclusions The high risk factors of EC in young women include menstrual dysfunction,sterility,polycystic ovarian syndrome(PCOS).The main therapy is surgery,young women desiring to preserve childbearing potential with well-differentiated grade I endometrial carcinoma can be treated by drug conservative therapy and helped to conceive under follow-up surveillance.
Keywords:young women    endometrial carcinoma    treatment    contraindication    side-effect    prognosis
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