Clinical Observation on Termination of Early Pregnancy of 213 Cases after Caesarian Section with Repeated Use of Mifepristone and Misoprostol

The aim was to investigate the efficacy and safety in women after cesarean section of termination of early pregnancy by treatment, or repeated treatment, with mifepristone and misoprostol. A total of 213 pregnant women with amenorrhea of 34-69 days after cesarean section who asked for medical abortion were recruited, including 63 cases undergoing their second medical abortion. A total amount of mifepristone of 150 mg, given in separate doses (4 doses of 25 mg following a first dose of 50 mg), was administered orally within 3 days, followed by misoprostol (0.6 mg orally) the morning of day 3. The complete abortion rate was 92.5%, while the incomplete abortion rate was 4.7% and the abortion failure rate was 2.8%. The sequential use of mifepristone and misoprostol could be successfully and repeatedly used for induced abortion in those women with a cesarean section history. Its efficacy was similar to that for the ordinary population. Its safety and effectiveness were satisfactory.