替考拉宁不良反应文献分析

目的：探讨替考拉宁不良反应发生原因和种类，为临床安全用药提供参考。方法：检索2000～2015年中国知网数据库、万方数据库、维普数据库等收载的国内期刊，进行回顾性分析和统计。结果：检索到有效病例19例，不良反应可发生在用药过程中和用药后各个时间段，且累及多个系统-器官，以过敏性反应（78.9%）居多，其次为泌尿系统损害（15.8%）、血液系统损害（10.5%）、神经系统损害（5.26%）。结论：临床医务人员应注意询问患者的过敏史，并结合患者的药敏结果使用该药；加强用药监测和药品不良反应监测。

Literature Analys is of 19 Adverse Drug Reaction Cases Induced by Teicoplanin

Objective: To discuss the causes and type of the adverse drug reaction (ADR) cases induced by teicoplanin in order to provide references for clinical rational drug use. Method: Search CNKI, Wanfang Data, CQVIP for published reports on teicoplanin causing ADR during 2000 and 2015 and the statistical analysis was performed.Result:19 valid cases were retrieved. ADR could happen in the course of medication or anytime after medication. ADR could involve multiple systems and organs. Most of ADR were allergic reaction(78.9%), followed by urinary system damage(15.8%), hematological system damage(10.5%), and nervous system damage (5.26%). Conclusion: Clinicians should pay attention to the allergy history of patients, apply medication with the drug susceptibility results and strengthen the monitoring of adverse drug reactions and drug monitoring.