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Multicenter evaluation of a rapid electrochemiluminescent adrenocorticotropic hormone (ACTH) immunoassay |
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| Authors: | Verschraegen Inge Anckaert Ellen Schiettecatte Johan Mees Marleen Garrido Adolfo Hermsen Derik Lentjes Eef G W M Liebert Andreas Roth Heinz-Jürgen Stamminger Gudrun Smitz Johan |
| Affiliation: | aLaboratory of Radioimmunology, Dutch-speaking Free University of Brussels (AZ-VUB), Laarbeeklaan 101, B-1090 Brussels, Belgium bInstitute of Clinical Chemistry and Laboratory Diagnostics, Heinrich-Heine-University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany cDepartment of Clinical Chemistry and Haematology, Lab Endocrinology, University Medical Center Utrecht, Postbox 85090, 3508 AB Utrecht, The Netherlands dCentre of Diagnostics, Klinikum Chemnitz, Flemmingstrasse 2, 09116 Chemnitz, Germany eLaboratory of Clinical Biochemistry, Hospital Donostia, Paseo Dr. Beguiristain, 114, 20014 San Sebastián, Spain fDepartment of Endocrinology, Laboratory Group Limbach, Im Breitspiel 15, 69126 Heidelberg, Germany |
| Abstract: | BACKGROUND: Measuring plasma adrenocorticotropic hormone (ACTH) is a key step in the differential diagnosis of hypothalamic-pituitary-adrenal disorders. METHODS: The recently developed electrochemiluminescence Elecsys ACTH immunoassay (Roche Diagnostics, Mannheim, Germany) was evaluated at six clinical laboratories on the Modular E170 and/or the Elecsys 2010 (Roche Diagnostics) immunoanalysers. RESULTS: The within-run and between-run imprecision was |
| Keywords: | Immunoassay Adrenocorticotropic hormone (ACTH) |
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