2型糖尿病患者生物阻抗式胃动力的测定

目的 观察2型糖尿病患者的胃动力情况并探讨其可能的影响因素.方法 采用基于小波转换的阻抗式胃动力采集系统检测65例2型糖尿病患者及30名健康志愿者的胃动力,并检测空腹血糖(FBG)和HbA1c.结果 65例2型糖尿病患者胃动力异常的发生率为53.85%,主要胃肠症状为腹胀、早饱、嗳气.2型糖尿病患者的胃动力主功率百分比较正常对照明显降低(P<0.05).HbA1c≥6.5%组患者的胃电主功率百分比较HbA1c<6.5%组显著降低(P<0.01).老年组胃动过缓功率百分比较青、中年组均显著增高(P<0.05).FBG及病程与2型糖尿病患者的胃动力障碍无关.结论 2型糖尿病患者胃动力障碍发生率高,HbA1c≥6.5%及老年患者更易发生胃动力障碍,FBG及病程与胃动力障碍无关.

Bio-impedance gastric motility in patients with type 2 diabetes mellitus

Objective To detect the gastric motility in patients with type 2 diabetes mellitus, and to explore the relationship between disorder of gastric motility in diabetes and the influential factors. Methods Sixty-five patients with type 2 diabetes mellitus and 30 health control subjects were collected. The gastric motility was tested with the signal processing device designed by Chongqing University of Posts and Telecommunications. The impedance and electrical signals were collected at the same time. Fasting blood glucose (FBG) was detected by oxidation enzyme method, while microcolumn method was adopted to test HbA1c. Results In the 65 patients with type 2 diabetes mellitus,the occurrence of abnormal gastric motility was 53.85% , they had several symptoms, such as abdominal distension, early satiety, and belching. The percentage of dominant frequency of impedance gastrogram in diabetes group was lower than that in the normal controls (P<0. 05 ). The percentage of dominant frequency of EGG in the abnormal HbA1c group( ≥6. 5% ) was significantly lower than that in the normal HbA1c group ( P<0. 01). The percentage of bradygastria in the elderly was higher than that in young and middle-aged subjects (P<0. 05), respectively. Disorder of gastric motility was not correlated with FBG and course of disease. Conclusions The incidence of disordered gastric motility is very high in patients with type 2 diabetes mellitus. Elderly patients and those with higher HbA1c are prone to suffer from disordered gastric motility. However, disorder in gastric motility is not correlated with FBG and duration of the illness.