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| 伴发副肿瘤性天疱疮的Castleman瘤——附10例报告 | |
| 引用本文： | 朱学骏,王京,陈喜雪,王仁贵,张澜波,李挺,王爱平,杨淑霞,涂平,李若瑜,吴艳,杨海珍,季素珍. 伴发副肿瘤性天疱疮的Castleman瘤——附10例报告[J]. 中华皮肤科杂志, 2005, 38(12): 745-747 |
| 作者姓名： | 朱学骏 王京 陈喜雪 王仁贵 张澜波 李挺 王爱平 杨淑霞 涂平 李若瑜 吴艳 杨海珍 季素珍 |
| 作者单位： | 1. 100034,北京大学第一医院皮肤性病科 2. 100034,北京大学第一医院医学影像科 3. 100034,北京大学第一医院普通外科 4. 100034,北京大学第一医院病理科 |
| 基金项目： | 国家自然科学基金资助项目(30371292)，2003年度高校博士点专项科研基金(20030001021) |
| 摘 要： | 目的了解Castleman瘤伴发副肿瘤性天疱疮的临床特点。方法分析总结我科诊治的10 例Castleman瘤伴发副肿瘤性天疱疮的临床特点和治疗方法。结果 Castleman瘤为我国最常见伴发副肿瘤性天疱疮的肿瘤,其临床表现、皮损和肿瘤的病理学特点、CT及免疫学特点都较独特。肿瘤切除手术中给予静脉滴注丙种球蛋白,对降低术后呼吸道症状的出现,使患者早日康复是有益的。结论由于肿瘤直接产生抗体致病,因此早期诊断、早期切除肿瘤,是成功治疗本病的关键。 |
| 关 键 词： | 副肿瘤性天疱疮 巨淋巴结增生 |
| 收稿时间： | 2004-07-16 |
| 修稿时间： | 2004-07-16 |
Castleman Tumor in Association with Paraneoplastic Pemphigus-A Report of 10 Cases |
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| ZHU Xue-jun,WANG Jing,CHEN Xi-xue,WANG Ren-gui,ZHANG Lan-bo,LI Ting,WANG Ai-ping,YANG Shu-xia,TU Ping,LI Ruo-yu,WU Yan,YANG Hai-zhen,JI Su-zhen. Castleman Tumor in Association with Paraneoplastic Pemphigus-A Report of 10 Cases[J]. Chinese Journal of Dermatology, 2005, 38(12): 745-747 | |
| Authors: | ZHU Xue-jun WANG Jing CHEN Xi-xue WANG Ren-gui ZHANG Lan-bo LI Ting WANG Ai-ping YANG Shu-xia TU Ping LI Ruo-yu WU Yan YANG Hai-zhen JI Su-zhen |
| Affiliation: | Department of Dermatology, Peking University First Hospital, Beijing 100034.China |
| Abstract: | Objective To obtain a better understaning of the clinical features of Castleman tumor associated paraneoplastic pemphigus. Methods The clinical features and therapy of 10 cases of this disease, diagnosed in the Department of Dermatology of Peking University First Hospital were analyzed. Results Castleman tumor was shown to be the most common neoplasm associated with paraneoplastic pemphigus in China. The clinical presentations, histopathologic characteristics, CT scan findings, and immunologic features were all unique. The early diagnosis and removal of the Castleman tumor are crucial for the treatment of this tumor-associated autoimmune disease. Conclusions Because Castleman tumor is directly related to the induction of autoimmunity, early diagnosis and prompt removal of the tumor are essential to the management of this disease. |
| Keywords: | Paraneoplastic Pemphigus Giant lymph node hyperplasia |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |