中西医结合治疗胃肠道肿瘤临床研究

目的：探析中西医结合治疗胃肠道肿瘤的临床疗效及对患者生存质量、化疗不良反应的影响。方法：将128例胃肠道肿瘤患者随机分为观察组和对照组,每组各64例。对照组予以奥沙利铂与5-氟尿嘧啶（5-FU）联合治疗,观察组在对照组的基础上加用参芪扶正注射液治疗。观察并比较两组患者临床疗效、生存质量情况及化疗不良反应的发生率。结果：观察组临床疗效有效率为50.0%,对照组临床疗效有效率为45.3%,两组差异无统计学意义（P〉0.05）;治疗后观察组KPS评分大幅度提高,显著高于对照组,差异有统计学意义（P〈0.05）;观察组恶心呕吐及白细胞减少发生率分别为62.5%和39.1%,显著低于对照组84.4%和62.5%,差异均有统计学意义（P〈0.05）。结论：中西医结合治疗胃肠道肿瘤有助于提高临床疗效、改善患者生存质量,减少化疗不良反应。

Clinical Research on Gastrointestinal Cancer Treated with Integrated Traditional Chinese and Western Medicine

Objective：To explore the clinical curative effect of integrated traditional Chinese and western medicine treatment of gastroin- testinal tumor and its influence on the quality of life, and adverse reaction of chemotherapy. Methods ：128 patients with gastrointestinal tumor were randomly divided into two groups with 64 cases in each group, and the control group was treated with oxaliplatin and 5-flu- orouraeil（5-FU） combination therapy, the observation group based on the therapy with Shenqi Fuzheng injection. Comparison of two groups of curative effect and quality of life, and the incidence of adverse reactions to chemotherapy. Results ： The total efficiency of the observation group was 50.0% higher than that of the control group 45.3% ,the difference was not statistically significant（ P 〉 0.05 ） ; after treatment, KPS score in the observation group increased greatly, and significantly higher than that in the control group, the differ- ence was statistically significant （P 〈 0.05 ） ;the incidence of adverse reaction of nausea and vomiting and leucopenia of the observation group were respectively 62.5% and 39.1% significantly lower than that of the control group 84.4% and 62.5% ,the differences were statistically significant（ P 〈 0.05 ）. Conclusion：Traditional Chinese medicine and western medicine treatment of gastrointestinal tumor is helpful to improve the clinical effect and improve the quality of life, and less adverse reaction.