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TPMT and MTHFR genotype is not associated with altered risk of thioguanine‐related sinusoidal obstruction syndrome in pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group
Authors:Lisa Wray MD  Marijana Vujkovic MSCE  PhD  Thomas McWilliams BSc  Shannon Cannon MD  Meenakshi Devidas PhD  Linda Stork MD  Richard Aplenc MD  MSCE   PhD
Affiliation:1. Division of Oncology, The Children's Hospital of Philadelphia, , Philadelphia, Pennsylvania;2. University of Wisconsin School of Medicine and Public Health, , Madison, Wisconsin;3. Department of Biostatistics, Colleges of Medicine and Public Health and Health Professions, University of Florida, , Gainesville, Florida;4. Division of Hematology‐Oncology, Doernbecher Children's Hospital/Oregon Health & Science University, , Portland, Oregon;5. Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, , Philadelphia, Pennsylvania
Abstract:
Keywords:acute lymphoblastic leukemia  MTHFR  SOS  thioguanine  TPMT  toxicity
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