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| 精索静脉高位结扎术对精子DNA碎片的影响 | |
| 引用本文： | Hu YY,Lin LZ,Li CD,Cai J. 精索静脉高位结扎术对精子DNA碎片的影响[J]. 中华男科学杂志, 2011, 17(10): 897-901 |
| 作者姓名： | Hu YY Lin LZ Li CD Cai J |
| 作者单位： | 温州医学院附属第一医院泌尿外科,浙江温州,325000 |
| 摘 要： | 目的:探讨精索静脉高位结扎术对精子DNA碎片影响及手术效果的评价。方法:精索静脉曲张(Varicocele,VC)患者34例,均行精索静脉高位结扎术。术前和术后3个月按WHO推荐方法进行精子运动指标(10项)、精子巴氏染色形态分析和精子DNA碎片分析检测。结果:VC患者术后正常精子形态比例明显高于术前,有显著性差异(P<0.01),术后精子DNA碎片比率、精子畸形指数(Sperm deformity index,SDI)和多种异常指数(Multiple anomalies index,MAI)均明显低于术前,有显著性差异(P<0.01);术后精子浓度、b级精子率均较术前升高,有显著性差异(P<0.05);术后a级精子比率、(a+b)级精子比率均比术前明显升高,有显著性差异(P<0.01)。VCⅠ级、Ⅱ级、Ⅲ级组术后精子DNA碎片比率均较术前明显降低,差异有统计学意义(P<0.01);亚临床型VC组术后精子DNA碎片比率与术前无显著差异(P>0.05)。VC术后大晕环精子比率较术前明显增多,有显著性差异(P<0.01);术后中晕环、小晕环、无晕环精子比率均较术前降低,有显著性差异(P<0.01)。结论:行精索静脉高位结扎术能有效改善VC患者的精子质量。 |
| 关 键 词： | 精索静脉曲张 精索静脉高位结扎术 精子DNA碎片 |
High ligation of the spermatic vein and sperm DNA fragmentation |
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| Hu Yang-yang,Lin Li-zhang,Li Cheng-di,Cai Jian. High ligation of the spermatic vein and sperm DNA fragmentation[J]. National journal of andrology, 2011, 17(10): 897-901 | |
| Authors: | Hu Yang-yang Lin Li-zhang Li Cheng-di Cai Jian |
| Affiliation: | HU Yang-yang,LIN Li-zhang,LI Cheng-di,CAI Jian Department of Urology,The First Hospital Affiliated to Wenzhou Medical College,Wenzhou,Zhejiang 325000,China |
| Abstract: | Objective: To investigate the effect of high ligation of the spermatic vein(HLSV) on DNA fragmentation in varicocele(VC) patients.Methods: Thirty-four VC patients underwent HLSV.Sperm motion indexes and the results of papanicolaou staining and DNA fragmentation detection were analyzed before and 3 months after the operation according to the WHO guidelines.Results: Compared with pre-operation,HLSV achieved a significant increase in the percentage of morphologically normal sperm(P<0.01),and remarkable decreas... |
| Keywords: | varicocele high ligation of the spermatic vein sperm DNA fragmentation |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |