全血肌钙蛋白T即时检测诊断急性心肌梗死的意义

目的探讨床边全血即时检测心肌肌钙蛋白T(cTnT)早期诊断急性心肌梗死(AMI)的临床意义和不良后果预测价值。方法对收入急诊抢救室的128例高度可疑的AMI患者24 h内抽取静脉血检测cTnT,同时用同一份标本分别检测肌酸激酶(CK)及其同工酶(CK-MB)活性。结果在发病6 h和24 h内cTnT检测AMI的敏感性分别为74.3%和97.1%,特异性为97.7%。而CK及CK-MB的活性6 h内检测AMI的敏感性分别为40%和35.7%。结论cTnT快速即时检测对诊断AMI具有高度的敏感性和特异性,该方法简单快速,适宜床边检测,有助于早期确诊AMI,特别适用于急诊及院前急救。

EXMINATION OF TOTAL BLOOD TROPONIN-T IN DIAGNOSING ACUTE MYOCARDIAC INFARCTION

Objective To explore the clinical value of examination of total blood myocardiac infarction in early diagnosing acute myocardiac infarction(AMI) and its predictive value in prognosis.Methods Examinations of venous blood from 128 cases of highly suspected AMI within 24 hours were made,and meanwhile,the same specimen was used to check creatine kinnase(CK) and the activity of isoenzyme.Results The sensitivity rates of troponin in examining AMI within 6 and 24 hours were 74.3% and 97.1% respectively,with the specificity being 97.7%.The sensitivity rates of CK and CK-MB within 6 hours were 40% and 35.7% respectively.Conclusion Troponin can have high sensitivity and specificity in examining AMI> This method can apply to emergency and first aid procedures.