Quality of life of Moroccan patients with celiac disease: Arabic translation,cross-cultural adaptation,and validation of the celiac disease questionnaire |
| |
| Affiliation: | 1. Hassan First University of Settat, Higher Institute of Health Sciences of Settat, Laboratory of Health Sciences and Technologies, Settat, Morocco;2. Cadi Ayyad University, Biosciences Research Laboratory, Faculty of Medicine and Pharmacy, Laboratory of Immunology, Center of Clinical Research, University Hospital Mohamed VI, Marrakech, Morocco;3. Cadi Ayyad University, Faculty of Medicine and Pharmacy of Marrakech, Gastroenterology and Diet department, Marrakech, Morocco;1. Department of Tropical Medicine, Ain Shams Center for Organ Transplantation (ASCOT), Ain Shams University, Cairo, Egypt;2. Department of General Surgery, Ain Shams Center for Organ Transplantation (ASCOT), Ain Shams University, Cairo, Egypt;1. Hepatology, Gastroenterology, and Infectious Diseases Department, Faculty of Medicine, Benha University, Benha, Egypt;2. Benha Fever Hospital, Benha, Egypt;3. Endemic Medicine and Hepato-gastroenterology Department, Faculty of Medicine, Cairo University, Egypt;4. Clinical and Chemical Pathology Department, Faculty of Medicine, Benha University, Benha, Egypt;5. Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Benha University, Benha, Egypt;1. Department of Gastrointestinal and Hepatobiliary Surgery, Shenzhen Longhua District Central Hospital, Shenzhen 518110, Guangdong, China;2. Department of Gastroenterology, Nansha Hospital, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou, China |
| |
| Abstract: | Background and study aimsCeliac disease (CD) management is based on a lifelong gluten-free diet (GFD) that affects the quality of life (QoL) of patients with CD. Specific instruments have been used to evaluate this QoL, such as the CD-Questionnaire (CD-Q). This study aimed to translate, validate, and cross-culturally adapt the CD-Q in an Arabic version and then apply it to evaluate the QoL of Moroccan adult patients with CD.Patients and methodsThe Moroccan version of the CD-Q (M?CD?Q) was administered to 150 patients with CD, and 112 of them completed it. The reproducibility and reliability of the M?CD?Q were studied by the intraclass coefficient (ICC) and Cronbach’s α, respectively. Parametric and nonparametric tests, confirmatory factor analysis, and Spearman correlation were used for the statistical analysis performed by SPSS, and the goodness-of-fit test was determined using SPSS AMOS.ResultsNo difficulties were found during the translation and cultural adaptation of the CD-Q. Cronbach’s α showed good internal consistency. The retest showed excellent reproducibility (ICC > 0.4). The study of the psychometric properties of the M?CD?Q showed good acceptance, zero ceiling effect, and floor effect. The model fit was good [(root mean square error of approximation = 0.075 (<0.08) and χ2 = 509.04, p < 0.001]. The total scores showed a neutral QoL. This QoL was worse in the worries subscale, which is related to gluten-free products. The GFD did not improve the QoL of the examined samples.ConclusionThe M?CD?Q is the first reliable and adapted instrument in an Arab country for the evaluation of QoL in patients with CD. CD negatively influences this QoL, especially items related to gluten-free products. |
| |
| Keywords: | Quality of life Celiac disease Gluten-free diet CD-Questionnaire Adaptation Morocco |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
