Assignment of the human locus determining phosphoglycolate phosphatase (PGP) to chromosome 16 |
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| Authors: | S. POVEY S. J. JEREMIAH R. F. BARKER D. A. HOPKINSON E. B. ROBSON P. J. L. COOK E. SOLOMON M. BOBROW B. CARRITT K. E. BUCKTON |
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| Affiliation: | MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London;The Genetics Laboratory, University of Oxford;Institute of Genetics, University of Glasgow;MRC Clinical and Population Cytogenetics Unit, Edinburgh |
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| Abstract: | ![]()
The segregation of human phosphoglycolate phosphatase has been studied in 52 independent human-rodent hybrids and 69 subclones. The results suggest that human PGP is on chromosome 16. Family data suggest that PGP is not close to 16qh or alpha Hp. The most likely regional assignment for PGP would appear to be 16p13 or 16p12, but a site on 16q cannot be entirely excluded. New data on 16qh and alpha Hp suggest that the male recombination fraction between these loci is about 0.2. |
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