Surgical treatment of malignant tumors in the biliopancreatoduodenal zone

Results of surgical treatment of 381 patients with cancer of biliopancreatoduodenal zone associated with obstructive jaundice were analyzed. Mean level of bilirubinemia was 182 +/- 12 mcmol/l. Cholecystoanastomosis was created in the majority of cases (51.4%). Radical surgery was carried out in 31 patients. Postoperative complications were seen in 155 (41%) patients. Renal-hepatic failure (28.1%) and purulent-septic complications (25.2%) were dominant. Lethality after radical operations was 12.9%, after palliative--15.7%. Inhibiting effect of autoplasma on phagocytosis and decrease of phagocytosis indexes 1.5-2 times are the risk factors of postoperative purulent-septic complications development. Discrete plasmapheresis reduces of postoperative purulent-septic complications rate.