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结直肠癌肝转移的新辅助治疗进展
引用本文:张甘露,袁俊波,赵长林. 结直肠癌肝转移的新辅助治疗进展[J]. 国际肿瘤学杂志, 2010, 37(11). DOI: 10.3760/cma.j.issn.1673-422X.2010.11.018
作者姓名:张甘露  袁俊波  赵长林
作者单位:大连大学附属新华医院肿瘤科,116021;大连大学附属新华医院肿瘤科,116021;大连大学附属新华医院肿瘤科,116021
摘    要:
目前,新辅助治疗已逐步应用到结直肠癌肝转移的治疗模式中.临床研究表明,新辅助化疗、新辅助放疗和新辅助放化疗可提高结直肠癌肝转移的手术切除率和根治性,对中下段直肠癌可术前降期、提高手术切除率、保肛率和降低复发率.新辅助治疗在结直肠癌肝转移综合治疗中具有较大的临床应用价值.

关 键 词:结直肠肿瘤  肿瘤转移  肿瘤辅助治疗  放射疗法

Advance in neoadjuvant chemotherapy for colorectal liver metastasis
ZHANG Gan-lu,YUAN Jun-bo,ZHAO Chang-lin. Advance in neoadjuvant chemotherapy for colorectal liver metastasis[J]. Journal of International Oncology, 2010, 37(11). DOI: 10.3760/cma.j.issn.1673-422X.2010.11.018
Authors:ZHANG Gan-lu  YUAN Jun-bo  ZHAO Chang-lin
Abstract:
Neoadjuvant therapy has been gradually applied to the treatment of colorectal liver metastasis in recent years. Many clinic researches indicate neoadjuvent chemotherapy, neoadjuvent radiotherapy and neoadjuvent chemoradiotherapy can improve surgical reaction rate and radical rate of colorectal liver metastasis,and can shrink the primary tumor and metastasis, improve the resection rate and sphincter preservation rate, and reduce the recurrence rate of locally advanced lower rectal cancer. Neoadjuvent therapy has great clinical practical value in the multi-modality treatment for colorectal metastasis.
Keywords:Colorectal neoplasms  Neoplasm Metastasis  Neoadjuvent therapy  Radiotherapy
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