脑血管病患者恢复期血脂水平的研究

为探讨血高密度脂蛋白胆固醇，载脂蛋白及脂蛋白「ＬＰ（ａ）」在脑血管病（ＣＶＤ）发病机理中的作用，对６８例ＣＶＤ患者和４８例非脑血管病患者（对照组）外周血ＨＤＬ－Ｃ，ａＰｏＡ１，ａＰｏＢ１００及ＬＰ（ａ）的含量进行了检测并做了对比研究。结果；发现ＬＰ（ａ）比ＨＤＬ０Ｃ，ａＰｏＡ１，Ｂ１００对ＣＶＤ的判别更敏感。

Study on Blood Fat Level in Patients with Ischemia Cerebrovascular Dise ases in Restoration Satge

In order to investigate the pathogenetic role of HDL-C. apolipoproteins (aPo) and lipoprotein (a) [LP(a)] in the cerebrovascular disease (CVD). the blood levels of HDL-C, aPoA1, aPoB100 and LP (a) were determined in 68 patients with CVD and 48 patients without CVD as control group and compared. The results showed that LP(a) in diagnosing CVD was more sensitive than HDL-C. aPoA1, aPoB100, The blood levels of HDL-C, aPoA1l,aPoB100 and the ratio of aPoA1 /aPoB100 in ischemia CVD were obviously decreased as compared with those in control group (P<0. 05 to 0. 01 ). while LP (a) was significantly increased (P<0. 001 ). The levels of aPo A1 and LP (a) in cerebral hemorrhage were markedly higher than in control group (P<0. 01 ). It was suggested that lower level of HDL-C or decreased aPo A1/B100 ratio may be one of the risk factors for ischemia CVD. High level of LP (a) was theindependent risk factor for ischemia stroke. aPo A1/B100 ratio and LP (a) level might be used as useful indicators for the prognosis of CVD.