骨痹膏治疗增生性脊柱炎的临床研究

为进一步验证经验药物骨痹骨的临床效果,将４１０例增生性脊柱炎患者随机分为３组。治疗组１１０例对照组１１０例,开放组１９０例,采用双盲法进行对照观察。经１个疗程（４周）治疗,从症状体征、实验室检查、药物反应几方面加以比较。结果显示总有效率治疗组和开放组均优于对照组;单项症疗效比较,在冬痛、压痛及功能活动等方面,治疗组优于对照组;病程不同者比较,治疗组与对照组有效率有明显差异;不同程度的患者比较,中度

A CLINICAL STUDY ON THE TREATMENT OF PROLIFERATIVE SPONDYLITIS BYGUBI GAO

To further test and verify the clinical therapeutic effect of GUBI GAO (GBG, Plaster for Arthralgia Syndrome of the Bone), an empiricmedicine, 410 cases of proliferative spondylitis were randomly divided into three groups: the treated (l 10 cases ), the control (110 cases ) and theopen (190 cases ). which were treated by confidential GBG. other drug, and non-confidential GBG, respectively. After 4--week (one-course )treatment, the three groups were compared in the symptoms and signs, laboratory examinations and drug reactions with the double blind method.The results showed: (1) The total effective rates of the treated and the open were better than that of the control (P < 0. of ) i (2) In singlesymptom therapeutic-effect comparison, the treated had an advantage over the control in the pains, tenderness. functional activity, etc; (3) Indifferent-diease-course comparison,the treated had a significant difference from the control in the effective rate(P<0.05).(4)In different-disease-severity comparison,the treated had and obvious difference from the control in the effective rate treatin the moderate or severe patient (P)has a good therapeutic effect on proliferative spondylitis but no side effect.