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冬虫夏草中砷及其安全性评价研究进展
引用本文:肖远灿,李岑,杨红霞,杜玉枝,张明,毕宏涛,魏立新.冬虫夏草中砷及其安全性评价研究进展[J].中草药,2021,52(15):4731-4740.
作者姓名:肖远灿  李岑  杨红霞  杜玉枝  张明  毕宏涛  魏立新
作者单位:中国科学院 西北高原生物研究所, 青海省藏药药理学和安全性评价研究重点实验室, 青海 西宁 810008;中国科学院藏药研究重点实验室, 青海西宁 810008;中国科学院大学, 北京 101408
基金项目:国家重点研发计划项目(2018YFC1708006);青海省重点实验室专项(2017-ZJ-Y08)
摘    要:传统名贵中药冬虫夏草Cordyceps sinensis中砷超标及其安全性问题近年来备受关注,针对冬虫夏草中砷的研究逐渐增加并不断深入。在文献查阅的基础上,从冬虫夏草砷及砷形态的分析方法,砷的含量、分布、存在形态,安全性评价,以及野生和人工仿生繁育冬虫夏草中砷含量等方面进行归纳总结,并对冬虫夏草中砷的认知及研究进行展望,以期为冬虫夏草安全性评价的深入研究提供参考。

关 键 词:冬虫夏草  总砷  砷形态  限量标准  未知结构砷  安全性评价
收稿时间:2020/11/10 0:00:00

Research progress on arsenic and its safety evaluation of Cordyceps sinensis
XIAO Yuan-can,LI Cen,YANG Hong-xi,DU Yu-zhi,ZHANG Ming,BI Hong-tao,WEI Li-xin.Research progress on arsenic and its safety evaluation of Cordyceps sinensis[J].Chinese Traditional and Herbal Drugs,2021,52(15):4731-4740.
Authors:XIAO Yuan-can  LI Cen  YANG Hong-xi  DU Yu-zhi  ZHANG Ming  BI Hong-tao  WEI Li-xin
Institution:Qinghai Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China;Key Laboratory of Tibetan Medicine Research, Chinese Academy of Sciences, Xining 810008, China;University of Chinese Academy of Sciences, Beijing 101408, China
Abstract:Excessive arsenic content and its safety problem of Dongchongxiacao (Cordyceps sinensis) attracted much more attention in recent years. The researches on arsenic of C. sinensis was increased and deepened gradually. Based on literatures reviewing, the analysis methods of arsenic and arsenic speciation, the data of concentration, distribution, existential form and safety evaluation of arsenic in C. sinensis were reviewed in this paper. Arsenic in natural and artificialbionic breeding C. sinensis was also compared. In view of current research work, the understanding and in-depth research of the arsenic in C. sinensis was prospected with aim of providing reference for further research on health safety evaluation of C. sinensis.
Keywords:Cordyceps sinensis (Berk  ) Sacc    arsenic  arsenic speciation  standard limit  unknown arsenic  safety evaluation
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