| 用于成骨细胞支架材料的部分脱蛋白骨细胞相容性的研究 |
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| 引用本文： | 李彦林,杨志明,韩睿,李世和,曾才铭. 用于成骨细胞支架材料的部分脱蛋白骨细胞相容性的研究[J]. 中国组织工程研究与临床康复, 2001, 5(24): 40-41 |
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| 作者姓名： | 李彦林 杨志明 韩睿 李世和 曾才铭 |
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| 作者单位： | 1. 昆明医学院第一附属医院,
2. 华西医科大学第一附属医院, |
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| 摘 要： | 目的探讨部分脱蛋白骨的细胞相容性 . 方法将猪肋骨用理化方法制得部分脱蛋白骨 ( PDB) , 检测其性能后 , 与成骨细胞体外复合培养 , 了解细胞相容性及细胞毒性 . 结果 PDB的主要成份为羟基磷灰石 , 蛋白质含量仅有原骨组织的 1/5, 具有原骨组织的网状孔隙结构系统 , 原骨组织骨盐支架的三维多孔结构存在 , 对人胚骨膜成骨细胞的形态特征、细胞周期、倍体水平无有害影响 . 结论 PDB具有原骨组织的网状孔隙结构系统 , 良好的细胞相容性 .
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| 关 键 词： | 部分脱蛋白骨 人胚骨膜成骨细胞 细胞相容性 |
| 文章编号： | 1007-5496(2001)12-0040-02 |
| 修稿时间： | 2001-08-01 |
Cellular compatibility study of partially deproteinised bone used as scalfolds of osteoblasts |
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| LI Yan-lin,YANG Zhi-ming,HAN Rui,et al.. Cellular compatibility study of partially deproteinised bone used as scalfolds of osteoblasts[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2001, 5(24): 40-41 |
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| Authors: | LI Yan-lin YANG Zhi-ming HAN Rui et al. |
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| Affiliation: | LI Yan-lin,YANG Zhi-ming,HAN Rui,et al.The First Affilited Hospital of Kunming Medical Colledge,Kunming 650031,China |
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| Abstract: | Objective To study the cellular compatibility of partially deproteinised bone.Method Partially deproteinised bone was processed by physical and chemical methods with pig ribs and its properties were examined,Then its cellular compatibility and cytotoxicity were examined by osteoblasts culture in vitro.Result The main ingredients of PDB was hydroxyapatite,its protein was only on fifth,and it had natural pore system which possessed pore network system of original bone.It has no bad affect on cell feature and cell cycle of human embryonic periosteal-derived osteoblasts composited with PDB.Conclusion PDB possessed original bone natural pore system and well cellular compatibility,and it could be used as scalfolds of osteoblasts. |
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| Keywords: | partially deproteinised bone human embryonic periosteal-derived osteoblasts cellular compatibility |
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