急性脑梗死病人雌二醇测定及其临床意义

①目的　了解急性脑梗死后雌二醇的变化规律。②方法　测定 1 66例急性脑梗死病人入院后第 1 ,7,1 4天雌二醇浓度 ,并与健康对照组比较。③结果　急性脑梗死病人雌二醇浓度低于健康对照组 (t =9.2 2 6 ,2 0 .2 4 8,P <0 .0 1 ) ,第 7天最低 ,第 1 4天已部分恢复 ;绝经前后及大小梗死灶间雌二醇浓度有显著性差异 (t =3 .432 ,4.1 62 ,P <0 .0 1 )。④结论　急性脑梗死病人雌二醇浓度测定可作为判断病情严重程度及预后的重要指标

MESUREMENT OF SERUM ESTRADIOL AND ITS SIGNIFICANCE FOR ACUTE CEREBRAL INFARCTION

Objective To study the changing law of e stradiol in acute cerebral infarction. Methods Serum estradiol levels were measured for 166 patients wit h acute cerebral infarction on day 1, day 7 and day 14 after admission, and the results were compared with those of the healthy control group. Results The serum estradiol levels in the cerebral infarctio n were lower than those of the healthy control group ( t=9.226,20.248, P <0.01); the lowest was found on day 7 and partially recovered on day 14. Th e difference of serum estradiol levels was found between pre and post menopau se patients and was also related to the size of the infarction focus ( t=3.432, 4.162,P<0.01 ). Conclusion The serum levels of estradiol may be used as an imp ortant parameter to evaluate the disease condition and predict the prognosis of patients with cerebral infarction. [