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Association Between Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Genetic Variants and Clinical Progression of Huntington's Disease
Authors:Romina Vuono PhD  Antonina Kouli MSc  Emilie M Legault BSc  Lauriane Chagnon DEC  Kieren S Allinson FRCPath  Alberto La Spada BSc  REGISTRY Investigators of the European Huntington's Disease Network  Ida Biunno PhD  Roger A Barker MRCP  PhD  Janelle Drouin-Ouellet PhD
Institution:1. John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom;2. Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada;3. Department of Pathology, Cambridge University Hospitals NHS (National Health Service) Foundation Trust, Cambridge, United Kingdom;4. Integrated Systems Engineering, Milano, Italy;5. Institute for Genetic and Biomedical Research - CNR, Milano, Italy
Abstract:
Keywords:cognitive decline  Huntington  inflammation  motor symptoms  TLR4  TREM2
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