6种针灸疗法治疗腹泻型肠易激综合征疗效的网状Meta分析

目的〓运用网状Meta分析方法比较6种针灸疗法治疗腹泻型肠易激综合征的临床疗效，为临床决策提供参考。方法 根据策略检索在Cochrane Library、Pubmed、Web of Science、中国知网、万方、维普数据库检索中关于6种针灸疗法治疗腹泻型肠易激综合征的文献，时间范围从建库至2020年7月。2位研究者独立根据纳入标准及排除标准进行筛选，数据提取及文献质量评价后再使用ADDIS、Stata软件进行网状Meta分析。结果 共纳入41篇文献，3 311例患者。网状Meta分析结果显示在治疗腹泻型肠易激综合征有效率上，针刺、温针、隔物灸、热敏灸优于西药及电针；温针、隔物灸优于针刺。6种针灸疗法有效率按从高到低排序依次为隔物灸、温针、热敏灸、针刺、艾灸、电针。结论 6种针灸疗法中隔物灸有效率最高，但受纳入文献数量及质量影响，结论仍有待进一步验证。

Network Meta-analysis of the Effect of Six Types Acupuncture Therapyin the Treatment of Diarrhea-predominant Irritable Bowel Syndrome

Objective To compare the clinical efficacy of six types acupuncture therapy for diarrhea-predominant irritable bowel syndrome by using network Meta-analysis, so as to provide reference for clinical decision-making. Methods Literatures on six types acupuncture therapy for diarrhea-predominant irritable bowel syndrome were retrieved from the Cochrane Library, Pubmed, Web of Science, CNKI, Wanfang and VIP database according to the strategies, and the time range was from inception to July 2020. The two researchers conducted screening independently according to inclusion criteria and exclusion criteria. After data extraction and literature quality evaluation, ADDIS and Stata software was used to conduct network Meta-analysis. Results A total of 41 articles and 3 311 patients were included. The results of network meta-analysis showed that acupuncture, warm acupuncture, indirect moxibustion and heat-sensitive moxibustion were superior to western medicine and electric acupuncture in the effective rate of treatment of diarrhea-predominant irritable bowel syndrome. Similarly, warm acupuncture and moxibustion are better than acupuncture. Six types acupuncture therapy in the order from high to low of the effective rate in treating diarrhea-predominant irritable bowel syndrome were: indirect moxibustion, warm acupuncture,heat-sensitive moxibustion, acupuncture, moxibustion and electric acupuncture. Conclusion Among the six acupuncture treatments, the indirect moxibustion has the highest effective rate. However, due to the influence of the quantity and quality of the included literature, the conclusion remains to be further verified.