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The role of the glycosaminoglycan layer in bladder defense mechanisms and interstitial cystitis
Authors:Dr C. Lowell Parsons
Affiliation:(1) Division of Urology, University of California, San Diego, California, USA;(2) Division of Urology, 8897, Department of Surgery, ECSD Medical School, 225 Dickinson Street, 92103-8897 San Diego, CA, USA
Abstract:
The bladder surface glycosaminoglycan layer is an important defense mechanism for the transitional epithelium. It allows adaptation to the constant exposure to urine, and controls the permeability of urinary substances to the transitional cell. This layer seems to be impaired in some patients with interstitial cystitis.
Keywords:Glycosaminoglycan layer  Interstitial cystitis  Transitional cell
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