自制膀胱控制器对截瘫犬膀胱功能的重建作用

目的：研究神经原位膀胱功能重建的电刺激治疗方法。方法：4只犬经T10平面造成截瘫后,在双侧S2神经根上植入刺激电极并通过导线与皮下的接收器连接,同时作硬膜内S1－S3后根切除。术后每天进行电刺激,观察截瘫犬的排尿情况,并进行膀胱造影检查。结果：4只犬均获得电刺激人工控制下排尿,排尿量80－140ml/次,排尿模式为刺激后排尿。膀胱造影发现膀胱充盈好,电刺激排尿过程中膀胱口张开,尿液排出,残余尿量约15－20ml。结论：自制膀胱控制器结合骶部去传入能很好地重建截瘫犬膀胱的贮尿和排尿功能。

Bladder controller in bladder function reconstruction of paraplegic dogs

Objective To observe whether bladder controller can restore bladder function in paraplegic dogs. Methods Four dogs were studied after their T 10 spinal cord was transected. Electrodes implanted around S 2 bilaterally were connected to subcutaneous recievers. Microsurgical techniques were employed in dorsal rhizotomy at S 1 3 intradural segment. After daily stimulation, the results of bladder controller were evaluated by micturition and vesicography. Results Micturition was given under electrical stimulation with a urine volume of 80 140 ml per time. The mode of micturition was post stimulus voiding. Vesicography showed that the bladder was filled and bladder neck was open in the micturition course of electric stimulation. Residual urine volume was 15 20 ml. Conclusion Bladder controller together with a sacral deafferentation procedure can restore bladder function of paraplegic dogs.