ENZYMES OF CATECHOLAMINE METABOLISM IN THE BRAINS OF RAT STRAINS DIFFERING IN THEIR PREFERENCE FOR OR TOLERANCE OF ETHANOL |
| |
| Authors: | PISPA, JAAKKO P. HUTTUNEN, MATTI O. SARVIHARJU, MAIJA YLIKAHRI, REINO |
| |
| Affiliation: | Department of Medical Chemistry, University of Helsinki, and Research Laboratories of the Finnish State Alcohol Company (Alko Ltd.) Helsinki, Finland |
| |
| Abstract: | The activities of the catecholamine-synthesizing and inactivatingenzymes were determined in whole brains of two pairs of ratstrains differing in their genetically-determined behaviouralresponses to ethanol. The alcohol-tolerant (AT) rats did notshow any significant differences in enzyme activities when comparedwith the non-tolerant (ANT) strain. The activity of tyrosinehydroxylase was found to be significantly higher in brains ofthe alcohol-preferring (AA) rats, than in those of the alcohol-non-preferring(ANA) strain. |
| |
| Keywords: | |
| 本文献已被 Oxford 等数据库收录！ |
|
