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Intraoperative radiotherapy (IORT) is an option for patients with localized breast recurrences after previous external-beam radiotherapy |
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| Authors: | Uta Kraus-Tiefenbacher Lelia Bauer Antonella Scheda Carola Schoeber Joerg Schaefer Volker Steil Frederik Wenz |
| Institution: | (1) Department of Radiation Oncology, Mannheim Medical Center, University of Heidelberg, Theodor-Kutzer Ufer 1-3, D-68167 Mannheim, Germany;(2) Department of Gynecology and Obstetrics, Mannheim Medical Center, University of Heidelberg, Theodor-Kutzer Ufer 1-3, D-68167 Mannheim, Germany;(3) Department of Clinical Radiology, Mannheim Medical Center, University of Heidelberg, Theodor-Kutzer Ufer 1-3, D-68167 Mannheim, Germany |
| Abstract: | BackgroundFor patients suffering of recurrent breast cancer within the irradiated breast, generally mastectomy is recommended. The normal tissue tolerance does not permit a second full-dose course of radiotherapy to the entire breast after a second breast-conserving surgery (BCS). A novel option is to treat these patients with partial breast irradiation (PBI). This approach is based on the hypothesis that re-irradiation of a limited volume will be effective and result in an acceptable frequency of side effects. The following report presents a single center experience with intraoperative radiotherapy (IORT) during excision of recurrent breast cancer in the previously irradiated breast. |
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