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| 早期应用低分子肝素钙预防危重儿DIC的临床研究 | |
| 引用本文： | 农淑萍,刘纯义,刘喜,洪先欧,罗勇. 早期应用低分子肝素钙预防危重儿DIC的临床研究[J]. 中国妇幼保健, 2006, 21(8): 1090-1091 |
| 作者姓名： | 农淑萍 刘纯义 刘喜 洪先欧 罗勇 |
| 作者单位： | 广东省深圳市宝安区妇幼保健院,518133 |
| 摘 要： | 目的:采用低分子肝素钙早期预防危重儿D IC评价其疗效。方法:将43例危重患儿作为研究对象,随机分为2组,治疗组23例,早期应用低分子肝素钙10 g/kg皮下注射,2次/d,连用3 d。对照组21例,不予低分子肝素钙预防,两组的其他治疗原则相同,观察两组病例出现D IC发生率及死亡率比较。结果:治疗组出现D IC发生率较对照组明显降低(P<0.01),死亡率较对照组明显降低(P<0.01),两组具有显著性差异。结论:早期应用低分子肝素钙能有效地预防危重儿D IC出现,并能降低危重儿死亡率。 |
| 关 键 词： | 低分子肝素钙 早期 危重儿 预防 DIC |
| 文章编号： | 1001-4411（2006）08-1090-02 |
| 收稿时间： | 2005-04-17 |
| 修稿时间： | 2005-04-17 |
Clinical study of low molecular weight heparin therapy used early in prevention of DIC in critically ill children |
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| NONG Shu - Ping, LIU Chun - Yi, LIU - Xi,et al.. Clinical study of low molecular weight heparin therapy used early in prevention of DIC in critically ill children[J]. Maternal and Child Health Care of China, 2006, 21(8): 1090-1091 | |
| Authors: | NONG Shu - Ping LIU Chun - Yi LIU - Xi et al. |
| Affiliation: | Department of Pediatrics, Baoan Region Maternity and Child Hospital of Shenzhen, Shenzhen 518133, Gnangdong, China |
| Abstract: | Objective:To investigate the therapeutic effect of low molecular weight heparin(LMWH) therapy in critically ill children to prevent disseminated intravascular coagulation(DIC).Methods:Forty-three severe patients were randomly divided into routine treatment group(n=22,given LMWH early,twice a day for 3 days,except routine treatment) and control group(n=21,routine treatment).The prevalence of DIC and mortality in two groups were observed and compared.Results:Incidence of DIC and mortality in treatment group were significant lower than those in control group(P<0.01).Conclusion:LMWH was applied early in severe patients,which could not only prevent efficiently DIC,also diminish mortality. |
| Keywords: | Low molecular weight heparin Early phases Criticallyill children Prevention Disseminated intravascular coagulation(DIC) |
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