妊娠期肝内胆汁淤积症126例临床分析

目的:探讨妊娠期肝内胆汁淤积症(ICP)的发生率、诊断及处理。方法:将126例ICP病例分治疗组(72例)和未治疗组(54例),对其临床资料进行回顾性分析。结果:治疗组羊水粪染、新生儿窒息、围生儿死亡、足月低体重儿、产后出血明显少于未治疗组。结论:对ICP进行早期诊断、早期治疗、适时终止妊娠能显著改善围生儿预后,提高母儿生存质量。

Clinical analysis of 126 Cases with intrahepatic cholestasis of pregnancy

Objective: To discuss the incidence,diagnosis and management of intrahepatic cholestasis of pregnancy(ICP).Methods: There were 126 cases with TCP in our hospital for nearly 6 years,72 in the treatment groups and 54 in the non-treatment groups,were analyzed retrospectively.Results: In treatment groups,meconium passage,asphyxia of newborn infants the incidence of perinatal mortality,full-term low-weight infants,postpartum hemorrhage were significantly lower than those in non-treatment groups.Conclusion: To diagnose and treat ICP early,optimal termination of pregnancy may significantly improve perinatal prongnosis and improve the survival quality of maternal and child.