脑卒中患者脂质代谢紊乱与中医辨证分型的关系

目的：分析脑卒中患者脂质代谢紊乱与中医辨证分型的关系。方法：脑卒中组１４２例和健康对照组１００例进行血脂、脂蛋白和载脂蛋白水平的测定。按中医辨证将脑卒中患者分３线：痰湿阻滞（ＰＤＳ）、阴虚阳亢（ＹＤＹＨ）和气虚瘀（ＱＤＢＳ）组。结果：ＰＤＳ和ＱＤＢＳ组患者血清总胆固醇（ＴＣ）、甘油三酯（ＴＧ）、高密度脂蛋白（ＨＤＬ）、低密度脂蛋白（ＬＤＬ）、载脂蛋白Ａ１、载脂蛋白Ｂ和ａｐｏＡ１／ａｐｏＢ等各项指标

Relationship between Lipometabolic Disorder in Stroke with TCM Syndrome Differentiation and Typing

Objective: To analyse the relationship between lipometabolic disorder in stroke with TCM Syndrome Differentiation and Typing. Methods: The serum lipid, lipoprotein and apo lipoprotein level of TCM treated group (142 cases) and control group (100 cases) were determined. The patients were subdivided into three Type groups according to TCM Syndrome Differentiation: Phlegm Dampness Stagnation (PDS), Yin Deficiency with Yang Hyperactivity (YDYH) and Qi Deficiency with Blood Stasis (QDBS) group. Results: The results showed that the level of TC, TG, HDL, LDL, apoA 1, apoB and apoA 1/apoB were significantly different in PDS and QDBS as compared with control group (P<0 05,P<0 01, respectively), while lipometabolic disorder of PDS was most serious in TCM Syndrome Differentiation of stroke. The level of TG, apoA 1/apoB were significantly different in YDYH in comparing with control group (P<0 05). While the level of TC, HDL, LDL and apoB were insignificantly different than those of control group (P>0 05). Conclusions: This study showed that lipometabolic disorder of stroke were correlated with Syndrome Differentiation of TCM. Stroke with PDS and QSBS should give removing Phlegm Dampness, dredging Meridian and removing blood stasis treatment besides routine treatment.