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107例慢性淋巴细胞性甲状腺炎并甲状腺腺瘤临床分析
引用本文:杨维良,张好刚,王惠良. 107例慢性淋巴细胞性甲状腺炎并甲状腺腺瘤临床分析[J]. 中国现代普通外科进展, 2008, 11(5)
作者姓名:杨维良  张好刚  王惠良
作者单位:1. 哈尔滨医科大学附属第二医院普通外科,黑龙江,哈尔滨,150086
2. 牡丹江市第二医院普通外科,黑龙江,牡丹江,157000
摘    要:目的:总结慢性淋巴细胞性甲状腺炎(chronic lymphadenoid thyroiditis,CLT)并甲状腺腺瘤(thyroid adenoma,TA)的诊治经验。方法:对107例CLT并TA的临床资料进行回顾性分析。结果:107例中,术前诊断为桥本病并TA38例,正确诊断率为35.5%(38/107),误诊、漏诊率为64.5%(69/107)。术中快速冷冻病理组织学检查确诊率为81.3%(87/107)。采用甲状腺部分、大部和次全切除术,81.3%(87/107)恢复良好;11.2%(12/107)出现声音嘶哑,治疗3个月后恢复;7.5%(8/107)出现手足抽搐,除1例治疗1年恢复外,其他7例患者均治疗2周后恢复。除3例双侧甲状腺全切除术患者需长期服用甲状腺素外,其余104例随访期间均未发生甲状腺功能减退。结论:CLT并TA诊断一旦确定,应积极手术治疗,根据术中快速病理组织学检查结果,选择手术方式和切除范围。术后根据FT3、FT4及TSH值可调整口服甲状腺素剂量。

关 键 词:慢性淋巴细胞性甲状腺炎  自身免疫学  甲状腺肿瘤  腺瘤

Clinical analysis of Hashimoto''s disease complicated with thyroid adenomas in 107 patients
YANG Wei-liang,ZHANG Hao-gang,WANG Hui-liang. Clinical analysis of Hashimoto''s disease complicated with thyroid adenomas in 107 patients[J]. Chinese Journal of Current Advances in General Surgery, 2008, 11(5)
Authors:YANG Wei-liang  ZHANG Hao-gang  WANG Hui-liang
Affiliation:YANG Wei-liang1,ZHANG Hao-gang1,WANG Hui-liang21Department of General Surgery,Second Affiliated Hospital of Harbin Medical University(Harbin 150086,China) 2Department of General Surgery,Second Hospital of Mudanjian city(Mudanjiang 157000,China)
Abstract:Objective:To summarize diagnosis and treatment of hashimoto's disease(HD) complicated with thyroid adenomas(TA) in 107 patients.Methods:Clinical data of 107 patients of HD complicated with TA were analysed retrospectively.Results:Complete serum immunologic examinations,B ultrasonography and fine needle aspiration biopsy were helpful for the diagnosis of HD with TA.Thirty-eight patients(35.5%) were diagnosed before operation.Misdiagnosis rate was 64.5%(69/107).Intraoperative frozen section diagnosis rate was...
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