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Highly-sensitive troponin I is increased in patients with gynecological cancers
Authors:Elisa Danese  Martina Montagnana  Silvia Giudici  Rosalia Aloe  Massimo Franchi  Gian Cesare Guidi  Giuseppe Lippi
Affiliation:1. Sezione di Biochimica Clinica, Dipartimento di Scienze della Vita e della Riproduzione, Università degli Studi di Verona, Verona, Italy;2. Unità di Ginecologia ed Ostetricia, Dipartimento di Scienze della Vita e della Riproduzione, Università degli studi di Verona, Italy;3. U.O. di Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero-Universitaria di Parma, Italy
Abstract:

Objectives

To investigate troponin I (TnI) in patients with gynecological cancers.

Methods

Highly-sensitive (HS) and conventional TnI were measured in 25 patients with untreated ovarian cancer, 25 with endometriosis and 25 with benign masses.

Results

Both HS and conventional TnI were increase in cancer patients. Values above the cut-off were found in 44% and 16% cancer patients using HS and conventional TnI methods, respectively.

Conclusions

Cardiac involvement is frequent in patients with gynecological cancers and should be preferably assessed using HS troponin immunoassays.
Keywords:Cancer   Gynecological cancer   Troponin   Highly-sensitive immunoassays
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