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Fusion proteins of flagellin and the major birch pollen allergen Bet v 1 show enhanced immunogenicity,reduced allergenicity,and intrinsic adjuvanticity |
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| Authors: | Claudia Kitzmüller Julia Kalser Sonja Mutschlechner Michael Hauser Gerhard J. Zlabinger Fatima Ferreira Barbara Bohle |
| Affiliation: | 1. Christian Doppler Laboratory for Immunomodulation, Department of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria;2. Institute of Immunology, Medical University of Vienna, Vienna, Austria;3. Department of Molecular Biology, University of Salzburg, Salzburg, Austria |
| Abstract: | |
| Keywords: | Allergen-specific immunotherapy adjuvant Toll-like receptor 5 flagellin Bet v 1 AIT Allergen-specific immunotherapy alum Aluminum hydroxide fliC mdDC Monocyte-derived dendritic cell SLIT Sublingual immunotherapy TCC T-cell clone TCL T-cell line TLR Toll-like receptor |
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