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胃神经内分泌肿瘤的诊断和治疗
引用本文:刘丹,沈琳,陆明. 胃神经内分泌肿瘤的诊断和治疗[J]. 临床肿瘤学杂志, 2015, 20(6): 549
作者姓名:刘丹  沈琳  陆明
作者单位:1 100142 北京 北京大学临床肿瘤学院 北京肿瘤医院暨北京市肿瘤防治研究所消化道肿瘤多学科协作组2 100142 恶性肿瘤发病机制及转化研究教育部重点实验室
摘    要:
胃神经内分泌肿瘤(G-NETs)是指来源于胃上皮及类肠嗜铬(ECL)细胞等神经内分泌细胞相关的肿瘤,占胃原发肿瘤一小部分,故长期以来对其认识局限,诊疗缺乏统一标准。但近年来G-NETs发病率较前明显升高,对其认识逐渐加深,临床根据G-NETs分化程度、与高胃泌素血症相关与否分为4个亚型,并针对不同亚型进行治疗。本文就近年来有关G-NETs流行病学、临床表现、诊断标准、治疗方法等最新进展做一综述,以期为G-NETs的诊疗提供参考。

关 键 词:胃神经内分泌肿瘤  高胃泌素血症  萎缩性胃炎  卓-艾综合征  类癌综合征
收稿时间:2014-10-22
修稿时间:2015-03-27

Diagnosis and treatment for gastric neuroendocrine tumors
LIU Dan,SHEN Lin,LU Ming. Diagnosis and treatment for gastric neuroendocrine tumors[J]. Chinese Clinical Oncology, 2015, 20(6): 549
Authors:LIU Dan  SHEN Lin  LU Ming
Affiliation:Multidisciplinary Collaboration Group, Pecking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing 100142, China
Abstract:
Gastric neuroendocrine tumors(G-NETs) arise in enterochromaffin-like(ECL) cells, which only account for a small part of gastric tumors. People have been less focused on them, so that the diagnosis and treatment of G-NETs are lack of acknowledged guidelines. However, with the increasing incidence, there is more deeply acknowledge in this field. In clinical, G-NETs are compromised of 4 subtypes according to differentiation and the relationship with hypergastrinemia. In the current review, we summarize the pathology, clinical characteristics, which aimed at treatment of it.
Keywords:Gastric neuroendocrine tumor(G-NETs)  Hypergastrinaemia  Atrophic gastritis  Zollinger-Ellison syn-drome  Carcinoid syndrome
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