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Interstitial Lung Disease in a Child with Antisynthetase Syndrome

Authors:	Don Hayes Jr. Peter B. Baker Heidi M. Mansour Mark E. Peeples Kathleen K. Nicol

Affiliation:	1. Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children’s Hospital, 700 Children’s?Drive, Columbus, 43205, OH, USA 2. Department of Pathology, The Ohio State University College of Medicine, Nationwide Children’s Hospital, Columbus, OH, USA 3. Department of Pharmaceutical Sciences, University of Kentucky College of Pharmacy, Lexington, KY, USA

Abstract:	Introduction Antisynthetase Syndrome is associated with interstitial lung disease in adult patients, but this has not been described in children. Materials and methods A 13-year-old with interstitial lung disease due to Antisynthetase Syndrome and pulmonary arterial hypertension underwent emergent bilateral lung transplantation after a rapid clinical decline. Conclusion We present the clinical, radiographic, and histological findings of a child with interstitial lung disease due to Antisynthetase Syndrome.

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