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深圳市宝安区2008-2009年孕产妇及新生儿梅毒患病情况分析
引用本文:鲁东平,王芬,张荣,李湘辉,梁瑞. 深圳市宝安区2008-2009年孕产妇及新生儿梅毒患病情况分析[J]. 中国皮肤性病学杂志, 2011, 25(3)
作者姓名:鲁东平  王芬  张荣  李湘辉  梁瑞
作者单位:1. 深圳市宝安区慢性病防治院皮肤科,广东,深圳,518133
2. 湖北省黄石市妇幼保健院,湖北,黄石,453000
摘    要:目的了解深圳市宝安区孕产妇及新生儿梅毒患病情况,为制定预防与控制梅毒发病和流行的策略提供依据。方法对236853例首次产前保健的孕产妇进行免费甲苯胺红不加热血清试验(TRUST)筛查,试验结果呈阳性者采用梅毒螺旋体明胶颗粒凝聚试验(TPPA)进行确认;其分娩的新生儿1个月内用TRUST,TPPA及19S-IgM-梅毒螺旋体明胶凝集试验(19S-IgM-TPPA)进行检测;对孕妇及新生儿确诊试验结果呈阳性者进行规范治疗,电话随访并进行健康教育。结果 818例孕产妇确诊为妊娠梅毒,患病率为3.45‰;孕妇首次筛查时间多数在孕28周以前;潜伏期梅毒占多数;死胎、死产和自然流产112例,75例终止妊娠;失访117例;多数孕产妇及新生儿TRUST的滴度≤1∶4,12例新生儿血清19S-IgM-TPPA检测阳性;分娩的415例新生儿主要是先天梅毒疑似病例,12例为先天梅毒,阳性率为2.89%。结论早期梅毒筛查、规范治疗、定期随访和科学管理妊娠梅毒是控制梅毒母婴传播的有效方法 。

关 键 词:孕产妇  新生儿  梅毒

Analysis on the Syphilis Infection of Pregnant Women and Neonates in Baoan District of Shenzhen from 2008 to 2009
LU Dong-ping,WANG Fen,ZHANG Rong,LI Xiang-hui,LIANG Rui. Analysis on the Syphilis Infection of Pregnant Women and Neonates in Baoan District of Shenzhen from 2008 to 2009[J]. The Chinese Journal of Dermatovenereology, 2011, 25(3)
Authors:LU Dong-ping  WANG Fen  ZHANG Rong  LI Xiang-hui  LIANG Rui
Affiliation:LU Dong-ping1,WANG Fen2,ZHANG Rong1,LI Xiang-hui1,LIANG Rui1 (1. Department of Dermatology,Baoan District Chronic Disease Hospital,Shenzhen 518133,China,2. Maternal and Child Health Hospital of Huangshi City,Huangshi 435000,China)
Abstract:Objective To survey status of pregnant women and neonates who infected syphilis in Baoan District of Shenzhen. and to provide the scientific proof for syphilis prevention and treatment strategies making. Methods A total of 236 853 initial antenatal care pregnant women were given a blood screen for syphilis by Toluidine Red Unheated Serum Test( TRUST) free,and the positive cases were confirmed by Treponema Pallidum Particle Assay( TPPA) ; Their neonates were detected by the same test and 19S-IgM-TPPA within ...
Keywords:Pregnant woman  Neonate  Syphilis  
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