The probability of a successful treatment of infertility by in-vitro fertilization |
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Authors: | Bouckaert, Andre Psalti, Iv Loumaye, Ernest De Cooman, Serge Thomas, Karl |
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Affiliation: | 1Unit of Medical Mathematics University of Louvain Brussels, Belgium 2Physiology of Human Reproduction Research Unit, Faculty of Medicine, University of Louvain Brussels, Belgium |
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Abstract: | The objective of this study was to define several estimatesof the success rate of in-vitro fertilization and embryo transfertreatment in relation to treatment outcome. The data were collectedin a retrospective study of 591 patients treated during 3 yearsin one Belgian university hospital. Several models used forevaluating the treatment of infertility were fitted to the data(logistic model, binomial model, double binomial model, exponentialmodel, the Speirs model. The number of oocytes retrieved andthe proportion of fertilized oocytes at the first attempt canbe used as prognostic factors. According to these factors, thesuccess rate after five attempts varies from 28 to 88% |
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Keywords: | embryo transfer/in-vitro fertilization/prognosis/statist-ical model |
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