Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice. |
| |
| Authors: | D M Williams G I Byrne B Grubbs T J Marshal J Schachter |
| |
| Affiliation: | Audie L. Murphy Memorial Veterans' Hospital, University of Texas Health Science Center, San Antonio 78284. |
| |
| Abstract: | ![]()
In a model of pneumonia caused by murine Chlamydia trachomatis, depletion experiments with monoclonal antibody to gamma interferon (IFN-gamma) made mice more susceptible. Repletion experiments giving exogenous recombinant murine IFN-gamma were not consistently protective. IFN-gamma may be necessary but not sufficient in host defense against the organism. |
| |
| Keywords: | |
|
